Journal: Journal of Advanced Research
Article Title: Machine learning and genetic algorithm-guided directed evolution for the development of antimicrobial peptides
doi: 10.1016/j.jare.2024.02.016
Figure Lengend Snippet: Results from the physicochemical property investigation and fitness matrix construction processes. a Results of the initial fitness matrix M 1 generated by PLSR and its derived final fitness matrix M 3 . b The Pearson correlation coefficient measurement indicates that the MICs and physicochemical properties are not simply linear. c and d FCM images indicating that LBD 1-8 were the largest clusters created with hydrophobicity ranging from 0.5 to 0.7, a net charge of 2 to 7, and an isoelectric point of 10 to 12.
Article Snippet: The MIC, net charge, hydrophobicity and isoelectric point of LBD 1-10 were clustered using FCM embedded in the FCM() function in MATLAB R2021b.
Techniques: Generated, Derivative Assay